Monthly Archives: July 2024

Registration for 2024 Canadian Science Policy Conference (CSPC): Empowering Society… in November 20 – 22, 2024

After celebrating its 15th anniversary in 2023 with an eye-watering price increase of over 20% for most categories (e.g., a standard registration rose from $990 to $1200 for the conference and gala dinner at the super saver rate; see my July 28, 2023 posting for more details), the Canadian Science Policy Conference (CSPC) has increased its prices by a little over 4% this year (e.g., $1250 for the conference and gala dinner at the super saver rate)..Of course, the inflation rate in Canada, according to the latest statistics (Statistics Canada June 25, 2024 news release) was 2.9% in May 2024.

Here are the currently available details about the 2024 conference, from the What To Expect webpage (apparently the conference is going be ‘spectacular’),

This year’s conference is in person from Nov 20th to 22nd [2024] with spectacular panels and programs.

CSPC 2024 features a spectacular program in different formats:

Wednesday, Nov 20th

8:00 am – 12:00 pm

Symposiums (5 themes)
(In Person Only)

Include 15+ sessions:

• Brain Strategy
• Braiding Knowledges Canada
• Equity,  Diversity and Inclusion
• Innovation Policy
• Youth Entrepreneurship

Thursday, Nov 21st – Friday, Nov 22nd

Main Conference
(In-Person Only)

• 50+ Concurrent Sessions
• 5 Plenary Sessions
• Three Luncheon Talks
• Three Breakfast Sessions
• Networking
• Gala Dinner

CSPC 2024 is expecting over 1000 participants, and 300+ speakers from across the globe, presenting in 50+ panel sessions covering a wide range of topics grouped in six tracks.

The conference will include a spectacular [emphasis mine] Gala Dinner featuring the Award Ceremony, which has become a signature annual event to celebrate Canadian science and innovation policy achievements.

CSPC 2024 attracts current and future leaders from all sectors and communities of science, innovation, technology, and policy across the country and internationally to discuss the challenges and solutions of our time.

Regarding Day 1, I can guess but really don’t know what ‘brain strategy’ or ‘braiding knowledges’ mean. Innovation is usually code for ‘business’, i.e., how can money be made? The other two seem self-explanatory.

Regarding Days 2 & 3, you can find our about the themes for the five conference tracks for the 50+ sessions on the CSPC 2024 Themes webpage.

Pricing

From the CSPC 2024 registration webpage,

Registration Rates

All rates are subject to 13% HST tax.

Conference and Symposiums: 3 Lunches, 3 breakfasts, refreshment breaks, and one reception. Gala Dinner is included in the Standard registration category.

SuperSaver
All summer – Sept 1st
Conference OnlyConference + Symposiums
Special SuperSaver Deal:
Symposium is Free up to $300 savings
Standard (Gala dinner included)$1250
Academic/Non-Profit/Diplomat/Retired$750
Student/Post Doctoral$250
Early Bird
Sept. 2nd – Oct. 5th
Conference OnlyConference + Symposiums
$200 savings
Standard (Gala dinner included)$1250$1350
Academic/Non-Profit/Diplomat/Retired$750$850
Student/Post Doctoral$300$350
Regular Rate
Oct 6th – Nov 16th
Conference OnlyConference + Symposiums
$200 savings
Standard (Gala dinner included)$1400$1500
Academic/Non-Profit/Diplomat/Retired$850$950
Student/Post Doctoral$350$400
Other (Conference Only)Cost
Speaker One Day (Day of presentation)$250
Speaker full conference (Conference + Symposiums)$500
Exhibitor Booth Staff$800
Symposiums Only (Wednesday, November 20th)Cost
Standard$300
Academic/Non-Profit/Diplomat/Retired$200
Student/Post Doctoral$100
Gala Dinner Tickets Only (Wednesday, November 20th)Cost
Conference Delegates (Students)$99
Conference Delegates (Academic / Non-profits)$150
Other (not registered for conference)$300
Table (10)$2750

Register Now!

Register Here (English)

Register Here (French)

To sum up, the 16th Canadian Science Policy Conference (CSPC) is being held November 20th-22nd, 2024, at the Westin Ottawa hotel. This is the second posting about the conference here, the first was my April 1, 2024 posting (scroll down to the “2024 Canadian Science Policy Conference (CSPC): call for proposals” subhead.

For anyone who isn’t familiar with the Canadian science police scene, these conferences are organized by the Canadian Science Policy Centre (CSPC). Yes, they use same abbreviation for the conferences and the centre.

New approach to brain-inspired (neuromorphic) computing: measuring information transfer

An April 8, 2024 news item on Nanowerk announces a new approach to neuromorphic computing that involves measurement, Note: Links have been removed,

The biological brain, especially the human brain, is a desirable computing system that consumes little energy and runs at high efficiency. To build a computing system just as good, many neuromorphic scientists focus on designing hardware components intended to mimic the elusive learning mechanism of the brain. Recently, a research team has approached the goal from a different angle, focusing on measuring information transfer instead.

Their method went through biological and simulation experiments and then proved effective in an electronic neuromorphic system. It was published in Intelligent Computing (“Information Transfer in Neuronal Circuits: From Biological Neurons to Neuromorphic Electronics”).

An April 8, 2024 Intelligent Computing news release on EurekAlert delves further into the topic,

Although electronic systems have not fully replicated the complex information transfer between synapses and neurons, the team has demonstrated that it is possible to transform biological circuits into electronic circuits while maintaining the amount of information transferred. “This represents a key step toward brain-inspired low-power artificial systems,” the authors note.

To evaluate the efficiency of information transfer, the team drew inspiration from information theory. They quantified the amount of information conveyed by synapses in single neurons, then measured the quantity using mutual information, the analysis of which reveals the relationship between input stimuli and neuron responses.

First, the team conducted experiments with biological neurons. They used brain slices from rats, recording and analyzing the biological circuits in cerebellar granule cells. Then they evaluated the information transmitted at the synapses from mossy fiber neurons to the cerebellar granule cells. The mossy fibers were periodically stimulated with electrical spikes to induce synaptic plasticity, a fundamental biological feature where the information transfer at the synapses is constantly strengthened or weakened with repeated neuronal activity.

The results show that the changes in mutual information values are largely consistent with the changes in biological information transfer induced by synaptic plasticity. The findings from simulation and electronic neuromorphic experiments mirrored the biological results.

Second, the team conducted experiments with simulated neurons. They applied a spiking neural network model, which was developed by the same research group. Spiking neural networks were inspired by the functioning of biological neurons and are considered a promising approach for achieving efficient neuromorphic computing.

In the model, four mossy fibers are connected to one cerebellar granule cell, and each connection is given a random weight, which affects the information transfer efficiency like synaptic plasticity does in biological circuits. In the experiments, the team applied eight stimulation patterns to all mossy fibers and recorded the responses to evaluate the information transfer in the artificial neural network.

Third, the team conducted experiments with electronic neurons. A setup similar to those in the biological and simulation experiments was used. A previously developed semiconductor device functioned as a neuron, and four specialized memristors functioned as synapses. The team applied 20 spike sequences to decrease resistance values, then applied another 20 to increase them. The changes in resistance values were investigated to assess the information transfer efficiency within the neuromorphic system.

In addition to verifying the quantity of information transferred in biological, simulated and electronic neurons, the team also highlighted the importance of spike timing, which as they observed is closely related to information transfer. This observation could influence the development of neuromorphic computing, given that most devices are designed with spike-frequency-based algorithms.

Here’s a link to and a citation for the paper,

Information Transfer in Neuronal Circuits: From Biological Neurons to Neuromorphic Electronics by Daniela Gandolfi, Lorenzo Benatti, Tommaso Zanotti, Giulia M. Boiani, Albertino Bigiani, Francesco M. Puglisi, and Jonathan Mapell. Intelligent Computing 1 Feb 2024 Vol 3 Article ID: 0059 DOI: 10.34133/icomputing.0059

This paper is open access.

Aerogels that are 3D printed from nanocellulose

The one on the far right looks a bit like a frog (to me),

Caption: Complexity and lightness: Empa researchers have developed a 3D printing process for biodegradable cellulose aerogel. Credit: Empa

An April 4, 2024 Swiss Federal Laboratories for Materials Science and Technology (EMPA) press release (also on EurekAlert) describes some interesting possibilities for nanocellulose,

At first glance, biodegradable materials, inks for 3D printing and aerogels don’t seem to have much in common. All three have great potential for the future, however: “green” materials do not pollute the environment, 3D printing can produce complex structures without waste, and ultra-light aerogels are excellent heat insulators. Empa researchers have now succeeded in combining all these advantages in a single material. And their cellulose-based, 3D-printable aerogel can do even more.

The miracle material was created under the leadership of Deeptanshu Sivaraman, Wim Malfait and Shanyu Zhao from Empa’s Building Energy Materials and Components laboratory, in collaboration with the Cellulose & Wood Materials and Advanced Analytical Technologies laboratories as well as the Center for X-ray Analytics. Together with other researchers, Zhao and Malfait had already developed a process for printing silica aerogels in 2020. No trivial task: Silica aerogels are foam-like materials, highly open porous and brittle. Before the Empa development, shaping them into complex forms had been pretty much impossible. “It was the logical next step to apply our printing technology to mechanically more robust bio-based aerogels,” says Zhao.

The researchers chose the most common biopolymer on Earth as their starting material: cellulose. Various nanoparticles can be obtained from this plant-based material using simple processing steps. Doctoral student Deeptanshu Sivaraman used two types of such nanoparticles – cellulose nanocrystals and cellulose nanofibers – to produce the “ink” for printing the bio-aerogel.

Over 80 percent water

The flow characteristics of the ink are crucial in 3D printing: Tt must be viscous enough in order to hold a three-dimensional shape before solidification. At the same time, however, it should liquefy under pressure so that it can flow through the nozzle. With the combination of nanocrystals and nanofibers, Sivaraman succeeded in doing just that: The long nanofibers give the ink a high viscosity, while the rather short crystals ensure that it has shear thinning effect so that it flows more easily during extrusion.

In total, the ink contains around twelve percent cellulose – and 88 percent water. “We were able to achieve the required properties with cellulose alone, without any additives or fillers,” says Sivaraman. This is not only good news for the biodegradability of the final aerogel products, but also for its heat-insulating properties. To turn the ink into an aerogel after printing, the researchers replace the pore solvent water first with ethanol and then with air, all while maintaining shape fidelity. “The less solid matter the ink contains, the more porous the resulting aerogel,” explains Zhao.

This high porosity and the small size of the pores make all aerogels extremely effective heat insulators. However, the researchers have identified a unique property in the printed cellulose aerogel: It is anisotropic. This means its strength and thermal conductivity are direction-dependent. “The anisotropy is partly due to the orientation of the nanocellulose fibers and partly due to the printing process itself,” says Malfait. This allows the researchers to control in which axis the printed aerogel piece should be particularly stable or particularly insulating. Such precisely crafted insulating components could be used in microelectronics, where heat should only be conducted in a certain direction.

A lot of potential applications in medicine

Although the original research project, which was funded by the Swiss National Science Foundation (SNSF), was primarily interested in thermal insulation, the researchers quickly saw another area of application for their printable bio-aerogel: medicine. As it consists of pure cellulose, the new aerogel is biocompatible with living tissues and cells. Its porous structure is able to absorb drugs and then release them into the body over a long period of time. And 3D printing offers the possibility of producing precise shapes that could, for instance, serve as scaffolds for cell growth or as implants.

A particular advantage is that the printed aerogel can be rehydrated and re-dried several times after the initial drying process without losing its shape or porous structure. In practical applications, this would make the material easier to handle: It could be stored and transported in dry form and only be soaked in water shortly before use. When dry, it is not only light and convenient to handle, but also less susceptible to bacteria – and does not have to be elaborately protected from drying out. “If you want to add active ingredients to the aerogel, this can be done in the final rehydration step immediately before use,” says Sivaraman. “Then you don’t run the risk of the medication losing its effectiveness over time or if it is stored incorrectly.”

The researchers are also working on drug delivery from aerogels in a follow-up project – with less focus on 3D printing for now. Shanyu Zhao is collaborating with researchers from Germany and Spain on aerogels made from other biopolymers, such as alginate and chitosan, derived from algae and chitin respectively. Meanwhile, Wim Malfait wants to further improve the thermal insulation of cellulose aerogels. And Deeptanshu Sivaraman has completed his doctorate and has since joined the Empa spin-off Siloxene AG, which creates new hybrid molecules based on silicon.

Fascinating work and here’s a link to and a citation for the paper,

Additive Manufacturing of Nanocellulose Aerogels with Structure-Oriented Thermal, Mechanical, and Biological Properties by Deeptanshu Sivaraman, Yannick Nagel, Gilberto Siqueira, Parth Chansoria, Jonathan Avaro, Antonia Neels, Gustav Nyström, Zhaoxia Sun, Jing Wang, Zhengyuan Pan, Ana Iglesias-Mejuto, Inés Ardao, Carlos A. García-González, Mengmeng Li, Tingting Wu, Marco Lattuada, Wim J. Malfait, Shanyu Zhao. Advanced Science DOI: https://doi.org/10.1002/advs.202307921 First published: 13 March 2024

This paper is open access.

You can find Siloxene AG here.

Could this discovery end global amphibian pandemic?

Caption: Panamanian golden frog is nearing extinction. Credit: Brian Gratwicke/U.S. Fish & Wildlife Service

An April 3, 2024 University of California at Riverside (also on EurekAlert) by Jules Bernstein describes the possibility of using a virus to infect a fungus that kills frogs worldwide, Note: A link has been removed,

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

The fungus, Batrachochytrium dendrobatidis or Bd, ravages the skin of frogs and toads, and eventually causes heart failure. To date it has contributed to the decline of over 500 amphibian species, and 90 possible extinctions including yellow-legged mountain frogs in the Sierras and the Panamanian golden frog. 

A new paper in the journal Current Biology documents the discovery of a virus that infects Bd, and which could be engineered to control the fungal disease.

The UC Riverside researchers who found the virus are excited about the implications of their discovery. In addition to helping them learn about how fungal pathogens rise and spread, it offers the hope of ending what they call a global amphibian pandemic. 

“Frogs control bad insects, crop pests, and mosquitoes. If their populations all over the world collapse, it could be devastating,” said UCR microbiology doctoral student and paper author Mark Yacoub. 

“They’re also the canary in the coal mine of climate change. As temperatures get warmer, UV light gets stronger, and water quality gets worse, frogs respond to that. If they get wiped out, we lose an important environmental signal,” Yacoub said. 

Bd was not prevalent before the late 1990s, but then, “all of a sudden frogs started dying,” Yacoub said.

When they found the Bd-infecting virus, Yacoub and UCR microbiology professor Jason Stajich had been working on the population genetics of Bd, hoping to gain a better understanding about where it came from and how it is mutating. 

“We wanted to see how different strains of fungus differ in places like Africa, Brazil, and the U.S., just like people study different strains of COVID-19,” Stajich said. To do this, the researchers used DNA sequencing technology. As they examined the data, they noticed some sequences that did not match the DNA of the fungus. 

“We realized these extra sequences, when put together, had the hallmarks of a viral genome,” Stajich said. 

Previously, researchers have looked for Bd viruses but did not find them. The fungus itself is hard to study because complex procedures are required to keep it alive in a laboratory. 

“It is also a hard fungus to keep track of because they have a life stage where they’re motile, they have a flagellus, which resembles a sperm tail, and they swim around,” Stajich said. 

Additionally, the virus that infects Bd was hard to find because most known viruses that infect fungi, called mycoviruses, are RNA viruses. However, this virus is a single-stranded DNA virus. By studying the DNA, the researchers could see the virus stuck in the genome of the fungus. 

It appears that only some strains of the fungus have the virus in their genome. But the infected ones seem to behave differently than the ones that don’t. “When these strains possess the virus they produce fewer spores, so it spreads more slowly. But they also might become more virulent, killing frogs faster,” Stajich said. 

Right now, the virus is essentially trapped inside the fungal genome. The researchers would eventually like to clone the virus and see if a manually infected strain of Bd also produces fewer spores.

“Because some strains of the fungus are infected and some are not, this underscores the importance of studying multiple strains of a fungal species,” Yacoub said. 

Moving forward, the researchers are looking for insights into the ways that the virus operates. “We don’t know how the virus infects the fungus, how it gets into the cells,” Yacoub said. “If we’re going to engineer the virus to help amphibians, we need answers to questions like these.”

In some places, it appears there are a few amphibian species acquiring resistance to Bd. “Like with COVID, there is a slow buildup of immunity. We are hoping to assist nature in taking its course,” Yacoub said. 

Here’s a link to and a citation for the paper,

An endogenous DNA virus in an amphibian-killing fungus associated with pathogen genotype and virulence by Rebecca A. Clemons, Mark N. Yacoub, Evelyn Faust, L. Felipe Toledo, Thomas S. Jenkinson, Tamilie Carvalho, D. Rabern Simmons, Erik Kalinka, Lillian K. Fritz-Laylin, Timothy Y. James, Jason E. Stajich. Current Biology Volume 34, ISSUE 7, P1469-1478.e6, April 08, 2024 DOI: https://doi.org/10.1016/j.cub.2024.02.062 Published online: March 14, 2024

This paper is open access.

Happy Canada Day! Breakdancing at the 2024 Paris Summer Olympics: physics in action + heat, mosquitoes, and sports

Happy July 1, 2024, also known as, Canada Day!

Onto breakdancing (or breaking), which for the first time will be an official event at the 2024 Paris Summer Olympics. Amy Pope, principal lecturer, physics and astronomy, Clemson University (South Carolina, US), has written a June 12, 2024 essay for The Conversation that describes breakdancing as physics in action, (h/t June 13, 2024 news item in phys.org), Note: Links have been removed,

Two athletes square off for an intense dance battle. The DJ starts spinning tunes, and the athletes begin twisting, spinning and seemingly defying gravity, respectfully watching each other and taking turns showing off their skill.

The athletes converse through their movements, speaking through a dance that celebrates both athleticism and creativity. While the athletes probably aren’t consciously thinking about the physics behind their movements, these complex and mesmerizing dances demonstrate a variety of different scientific principles.

Breaking, also known as breakdancing, originated in the late 1970s in the New York City borough of the Bronx. Debuting as an Olympic sport in the 2024 Summer Olympics, breaking will showcase its dynamic moves on a global stage. This urban dance style combines hip-hop culture, acrobatic moves and expressive footwork.

Since its inception, breaking has evolved into a competitive art form. An MC narrates the movements, while a DJ mixes songs to create a dynamic atmosphere. The Olympics will feature two events: one for men, called B-boys, and one for women, called B-girls. In these events, athletes will face off in dance battles.

… Success in this sport requires combining dance moves from three basic categories: top rock, down rock and freeze.

And now for the physics of it all, from Pope’s June 12, 2024 essay, Note: Links have been removed,

Top rock moves [emphasis mine] are performed while standing up, focusing on fancy footwork and hand movements. These movements are reminiscent of hip-hop dancing.

Top rock moves rely on having lots of friction between an athlete’s shoes and the floor. Friction is the force [emphasis miine] that resists when you slide something across a surface.

This friction allows the athlete to take very quick steps and to stop abruptly. The dancers must intuitively understand inertia, or the fact that their bodies will continue in the direction they’re moving unless they are acted upon by an external force. To stop abruptly, athletes need to engage their muscles, getting their shoes to grip the ground to stop themselves from continuing forward.

Down rock moves [emphasis mine] are performed while on the floor. Athletes may spin in circles with their head, back, elbows or shoulders touching the ground and their feet in the air. B-boys and B-girls rely heavily on an internal knowledge of physics to complete these moves.

Consider the physics of a backspin. A backspin occurs when the athlete is on their back with their feet lifted in the air, rotating around a specific area of their back.

Sitting on the floor, the athlete’s left foot stays in contact with the floor while they spread their right leg wide, gathering linear momentum [emphasis mine] as they sweep their right leg toward their left foot in a wide arc. Then, they release their left leg from contact with the ground and roll onto their back.

Now that only their back is in contact with the ground, the linear momentum from their leg turns into angular momentum [emphasis mine], which rotates the athlete around an axis that extends upward from their back’s contact point with the ground. This move turns magical when they bring their legs and arms inward, toward the axis of rotation. This principal is called conservation of angular momentum.

When an athlete brings their mass in more closely to the axis of rotation, the athlete’s rotations speed up. Extending their legs and arms once again and moving their mass away from the axis of rotation will cause the competitor to slow their rotation speed down. Once they slow down, they can transition to another move.

Freeze [emphasis mine] occurs when athletes come to a stop in a funky pose, often occurring in time to the music and in an upside-down position. To freeze effectively, the athlete must have full control over their center of mass, placing it right above the point of their body that is in contact with the floor. The center of mass is the average position of all the parts of an athlete, weighted according to their masses. The “balance point” where the entire mass of the athlete seems to be concentrated is the center of mass.

Athletes are most stable when their center of mass is as close to the ground as possible. You will see many competitors freeze with arms bent in an effort to lower their center of mass. This lowered center of mass reduces their distance from the floor and minimizes the tendency of their body to rock to one side or the other due to torque.

Torque is a twisting force [emphasis mine], like the force used to turn a wrench. The torque depends on two things: the amount of force you apply, and how far from the pivot point you apply the force. With an athlete’s center of mass closer to the ground, the athlete decreases the distance between the pivot point – the ground – and where the force of gravity is applied – the athlete’s center of mass.

Athletes need great strength to halt their motion mid-movement because they have to apply a force to resist the change in inertia.

It’s not just about the moves, clothing is a factor, Pope’s June 12, 2024 essay,

Many sports require a specific uniform. Breaking doesn’t – an athlete can wear whatever they want – but the right outfit will maximize their chance of success.

The athlete wants a shirt that minimizes the friction between their body and the ground during a spin. Lettering or images on the back of the shirt will add friction, which hinders an athlete’s ability to perform some down rock moves. An athlete may choose to wear long sleeves if they plan to slide on their elbows, as bare skin in contact with the floor provides more friction.

Athletes also have to think about the headgear they wear. …

There’s a bit more information about the breakdancing competition on the 2024 Olympics website.I cannot find a full list of athletes for the August 9, 2024 (B-Girls) and August 10, 2024 (B-Boys) competitions. There is this June 2, 2024 article (from the Associated Press) on the CBC (Canadian Broadcasting Corporation) online news website,

Victor Montalvo (B-boy Victor), United States: A breaker who describes himself as a student of old school b-boys from the founding era of hip-hop, the 30-year-old Montalvo, who is from Kissimmee, Florida, qualified for Paris by besting all other b-boys at the 2023 WDSF World Breaking Championship in Belgium.

Sunny Choi (B-girl Sunny), United States: The 35-year-old Choi, a cheerful Queens, New York-bred breaker, has long been an ambassador for b-girls globally. She qualified for the Paris Games with her win at the 2023 Pan American Games in Chile.

Philip Kim (B-boy Phil Wizard), Vancouver, Canada: Consistently ranked in the top three b-boys in the international breaking competitive community, Kim secured a spot for Paris when he came out on top at last year’s Pan American Games.

Dominika Banevič (B-girl Nicka), Lithuania: Banevič was the youngest in her category at last year’s WDSF World Breaking Championship, when she punched her ticket to Paris. Banevič turns 17 this month.

I thought the competition would be dominated by Americans and certainly wasn’t expecting to see a Lithuanian (Dominika Banevič or ‘Nicka’) listed as a competitor to watch. The Canadian (Philip Kim or ‘Phil Wizard’) is also a surprise. Who knew Vancouver was home to a leading B-boy?

Two comments: heat and mosquitoes (dengue and other fevers)

The organizers of the Paris 2024 Summer Olympics are to be complimented for their work towards making the games ‘green’ but that is a complex process.

Heat

For example, the Canadian Broadcasting Corporation (CBC) ran a news item on The National news telecast on June 17, 2024 (see telecast for embedded video clip) regarding concerns about and preparations for heat,

Preparing for extreme heat at the Paris Olympics

Paris Olympic organizers plan to make this summer’s games the greenest ever, but that includes offering less air conditioning to cut down on energy use. [emphases mine] As temperatures rise globally, some suggest the organizers should take extreme heat into account when awarding cities with the next big Olympic games.

Some of the reporting in the CBC news item is based on information from a June 18, 2024 University of Portsmouth (UK) press release, Note: Links have been removed,

Leading athletes are warning that intense heat at the Paris Olympics in July-August 2024 could lead to competitors collapsing and in worst case scenarios dying during the Games. [emphasis mine]

Eleven Olympians, including winners of five World Championships and six Olympic medals, have come together with climate scientists and leading heat physiologists Professor Mike Tipton and Dr Jo Corbett from the University of Portsmouth to unpack the serious threat extreme heat poses for athletes in a new Rings of Fire report.

Dr Corbett, Associate Professor of Environmental Physiology in the School of Sport, Health and Exercise Science at the University of Portsmouth, said: “A warming planet will present an additional challenge to athletes, which can adversely impact on their performance and diminish the sporting spectacle of the Olympic Games,. Hotter conditions also increase the potential for heat illness amongst all individuals exposed to high thermal stress, including officials and spectators, as well as athletes.”

“For athletes, from smaller performance-impacting issues like sleep disruption and last-minute changes to event timings, to exacerbated health impacts and heat related stress and injury, the consequences can be varied and wide-ranging. With global temperatures continuing to rise, climate change should increasingly be viewed as an existential threat to sport,” said Lord Sebastian Coe, President of World Athletics and four-time Olympic medallist.

The Tokyo Games became known as the “hottest in history,” with temperatures exceeding 34°C and humidity reaching nearly 70 per cent, leading to severe health risks for competitors. The Paris Games have the potential to surpass that, with climate change driven by the burning of fossil fuels contributing to record heat streaks during the past months.

2023 was the hottest year on record according to the EU’s [European Union] Copernicus Climate Change Service and 2024 has continued this streak. April 2024 was warmer globally than any previous April in the record books, said experts at Copernicus.

The Rings of Fire report discusses the deadly heatwave in France in 2003 – which killed over 14,000 people – and subsequent years of record-breaking temperatures, exceeding 42°C. It underscores the heightened risk of extreme heat during the Paris Olympics, especially considering the significant rise in the region’s temperatures since the city last hosted the Games a century ago.

You can find the Rings of Fire report here and the Corpernicus Climate Change Service here.

Mosquitoes and dengue and other fevers

Obviously, the world is changing as you can see in this June 18, 2024 Institut Pasteur press release (also on EurekAlert),

Olympics: how many days does it take for mosquitoes in Greater Paris to transmit arboviruses, and what preventive measures are needed?

The number of imported cases of dengue in the Greater Paris region increased significantly in the first few months of 2024. In the run-up to the Olympic Games, with huge numbers of international visitors set to come to Paris – especially from endemic dengue countries –, we need to be vigilant. Scientists from the Institut Pasteur, in collaboration with the Regional Mosquito Control Agency (ARD) and the National Reference Center for Arboviruses (Inserm-Irba), have demonstrated that the tiger mosquito, now present in Greater Paris, is capable of transmitting five viruses (West Nile, chikungunya, Usutu, Zika and dengue) within different time frames ranging from 3 to 21 days, at an external temperature of 28°C. These results highlight the importance of stepping up surveillance of imported cases of arboviruses this summer. The study was published on May 16 [2024] in Eurosurveillance.

Between January 1 and April 19, 2024, 1,679 imported dengue cases were reported in mainland France, 13 times more than the number reported over the same period the previous year (source SPF). It is likely that this number will increase during the Olympic Games, as more people come to Paris from countries that are endemic regions for other arboviruses. The vector for dengue transmission is Aedes albopictus, more commonly known as the tiger mosquito. Arboviruses are transmitted when a female mosquito bites a virus carrier and ingests viral particles. One particular feature of arboviruses is that they can replicate in mosquitoes (unlike other viruses such as influenza, which are destroyed when ingested by mosquitoes). The viral particles multiply and spread within the mosquito, reaching the salivary glands in a few days. When the female mosquito bites another human, she injects the virus while taking her blood meal.

The tiger mosquito is now present in 78 départements in mainland France, and this together with other climate change-related factors is facilitating vector-borne transmission. Scientists from the Institut Pasteur’s Arboviruses and Insect Vectors Unit, in collaboration with the Regional Vector Control Agency (ARD) and the National Reference Center for Arboviruses (Inserm-Irba), therefore decided to analyze the ability of Aedes albopictus in Greater Paris to transmit five arboviruses at a temperature of 28°C, which is likely in the region at this time of year, and counted the number of days between initial infection and the possibility of the virus being transmitted through a further mosquito bite. As well as the dengue, chikungunya and Zika viruses, which we already know can be transmitted by the tiger mosquito, the scientists studied the Usutu and West Nile viruses, which are naturally transmitted by another mosquito species, Culex pipiens (known as the “common mosquito”). Culex pipiens mosquitoes transmit viruses to humans after feeding on birds, which act as viral reservoirs.

Tiger mosquito susceptible to five arboviruses

Working in a BSL3 laboratory, the scientists studied the ability of tiger mosquitoes to transmit these five viruses and determined the extrinsic incubation period required for the virus to reach the mosquito’s salivary glands in sufficient quantities to infect a human. At 28°C, West Nile virus needs three days before it can be transmitted to humans by mosquitoes. The incubation period is 3 to 7 days for chikungunya and Usutu, and 14 to 21 days for dengue and Zika.(1) 

This information is crucial to gage the additional risk represented by the upcoming Olympic Games in Paris, which will see significant intermingling of populations combined with the return of travelers from endemic regions and a season conducive to mosquito proliferation. The findings can also be used to develop suitable control strategies.

“If a case of dengue is detected in the Greater Paris region, we now know that disinsection is required within 21 days. We can use these results to adjust our time frame for action and optimize our approach,” explains Anna-Bella Failloux, Head of the Institut Pasteur’s Arboviruses and Insect Vectors Unit, who led the study. “Depending on the temperatures we experience in and around Paris this summer, our findings will be essential for adjusting control measures as needed.”

What precautions should be taken in the run-up to the Olympics?

Health care professionals are trained to detect the symptoms of arboviruses if people indicate that they have recently been to an endemic country. The difficulty of surveillance is that many cases are asymptomatic: although dengue is a notifiable disease, up to 80% of cases lead to few or no symptoms. If a diagnosis of one of these diseases is confirmed, an inquiry is carried out by France’s Regional Health Agencies to determine where the individuals live or spent time in the days before the diagnosis, so that they can identify the areas where disinsection is needed. Anyone coming back from a foreign trip who experiences fever or aches is advised to see their family physician immediately and indicate the region they recently returned from.

“The alert system in France is effective. The applicable procedure and measures are already well established because France’s overseas territories in endemic regions have provided us with expertise in these diseases and know-how on epidemiological monitoring. My team is affiliated with the Arbo-France network, and we are contacted as soon as an arbovirus is detected,” continues Anna-Bella Failloux.

Since 2006, vector control measures in France have led to increased surveillance of tiger mosquitoes between May 1 and November 30 each year. This involves monitoring mosquito populations in areas where they are likely to be present; disease surveillance coordinated by Santé publique France based on reporting of viruses such as dengue, chikungunya and Zika by health care professionals; and raising awareness among people living in areas where mosquitoes have been reported. France’s Regional Health Agencies (ARS) and their operators are responsible for managing reporting, monitoring the presence of mosquitoes and taking rapid action in response to human cases of infection (vector control).

This research, which focused on mosquitoes in the Greater Paris region for this first study, will soon be extended to the rest of mainland France. Extrinsic incubation periods vary from one tiger mosquito population to the next because of differences in their genetic makeup and in local temperatures. 

Find out more:

Video: “We are going to have to learn to live with tiger mosquitoes” – Anna-Bella Failloux

Disease-carrying mosquitoes – French Ministry of Employment, Health and Solidarity (sante.gouv.fr)

  1. It is important to point out that for Usutu and West Nile, the ability of tiger mosquitoes to transmit these viruses to humans in real-life conditions, outside the experimental setting, is yet to be demonstrated, as they are naturally transmitted by Culex pipiens, another mosquito species.

Here’s a link to and a citation for the paper,

Aedes albopictus is a competent vector of five arboviruses affecting human health, greater Paris, France, 2023 by Chloé Bohers, Marie Vazeille, Lydia Bernaoui, Luidji Pascalin, Kevin Meignan, Laurence Mousson, Georges Jakerian, Anaïs Karchh, Xavier de Lamballerie, Anna-Bella Failloux. Euro Surveill. 2024; 29 (20): pii=2400271. DOI: https://doi.org/10.2807/1560-7917.ES.2024.29.20.2400271

This paper is open access.

I covered the movement of dengue fever and malaria into the Northern Hemisphere in an August 10, 2023 posting,

The World Health Organization (WHO) notes that dengue fever cases have increased exponentially since 2000 (from the March 17, 2023 version of the WHO’s “Dengue and severe dengue” fact sheet),

Global burden

The incidence of dengue has grown dramatically around the world in recent decades, with cases reported to WHO increased from 505 430 cases in 2000 to 5.2 million in 2019. A vast majority of cases are asymptomatic or mild and self-managed, and hence the actual numbers of dengue cases are under-reported. Many cases are also misdiagnosed as other febrile illnesses (1).

One modelling estimate indicates 390 million dengue virus infections per year of which 96 million manifest clinically (2). Another study on the prevalence of dengue estimates that 3.9 billion people are at risk of infection with dengue viruses.

The disease is now endemic in more than 100 countries in the WHO Regions of Africa, the Americas, the Eastern Mediterranean, South-East Asia and the Western Pacific. The Americas, South-East Asia and Western Pacific regions are the most seriously affected, with Asia representing around 70% of the global disease burden.

Dengue is spreading to new areas including Europe, [emphasis mine] and explosive outbreaks are occurring. Local transmission was reported for the first time in France and Croatia in 2010 [emphasis mine] and imported cases were detected in 3 other European countries.

The researchers from the University of Central Florida (UCF) couldn’t have known when they began their project to study mosquito bites and disease that Florida would register its first malaria cases in 20 years this summer, …

It seems pretty clear that there’s increasing concern about mosquito-borne diseases no matter where you live.

It looks like mega-sports events attract more visitors than you might expect.